Efectos adversos de la vacuna AH1N1 en los pacientes crónicos y embarazadas inscritos en el centro de salud del área no. 3, Cuenca 2010

Abstract

ABSTRACT Objetive: Determine the adverse effects of the vaccine influenza A H1N1 in chronic patients and pregnant women registered in Health Area Center No. 3.

Methods and materials: The present study is descriptive. The universe are N= 442 patients. It was used the structured interview applying a questionnaire consisting of socio-demographic variables, also the test “European Medicines Agency en la European Strategy for Influenza A/H1N1 Vaccine Benefit-Risk Monitoring”. The results had a statistical analysis in Microsoft Excel software version 2010. Results: In our study we found that 71.04% (314 patients) were female and 28.96% (128 patients) were male sex. Of all women, 100 of them, ie 22.62% of the universe were in some gestation stage, although the 342 patients corresponding the 77.38% have some chronic disease. The Celtura Vaccine was the most used equivalent to the 83.48%, although the 16.52% received Monovalent vaccine. From the total of the patients who received the vaccine, only the 25.11% which corresponds to 111 patients showed some adverse effect. Pain and inflammation were the most frequent with the Celtura Vaccine in a 47.62%, and the 56.67% with Monovalent Vaccine. In this study, there wasn’t presence a Guillain Barré Syndrome, compared to studies directed in other countries like Korea and Brazil.

Conclusions: The Influenza A H1N1’s vaccine produces the same adverse effects than the Common Influenza. From the four people vaccinated, one presented some adverse effect. The pain and the inflammation were the most adverse effect where they received the vaccine. About chronic adverse effects in this study, there were none.