Asociación entre las pruebas de función tiroidea y características tumorales en cáncer de tiroides en el Instituto del Cáncer SOLCA Cuenca. 2010-2018

Abstract

Background Thyroid cancer is the most common malignant endocrine neoplasm. The increase in its incidence requires the development of new tools that allow establishing an adequate and timely treatment. Objective To determine the association between thyroid function tests and tumor characteristics in thyroid cancer at the SOLCA Cuenca Cancer Institute in the 2010-2018 period. Methodology Cross-sectional and analytical study based on the clinical histories of patients with thyroid cancer and thyroid function tests performed at SOLCA Cuenca, 2010-2018, through a specifically designed form, being processed and analyzed with the SPSS program. The results are presented in tables of frequencies, percentages, means, standard deviation, chi-square with a p <0.05 and prevalence ratio with a 95% confidence interval. Results Thyroid cancer affected women 6.72 times more than men, with an average of 46 ± 15 years. The most frequent histological type was papillary, finding a size ≥ 1cm in 85.3% of cases, bilaterality in 36.3%, multifocality / multicentricity in 39.8%, vascular invasion in 66.2%, extrathyroid invasion in 39.1%, lymph node metastasis in 61.9% and distant metastasis in 4.1% of cases. Higher levels of TSH were associated with the presence of bilaterality (p = 0.024), multifocality (p = 0.027) and extrathyroid invasion (0.022). Conclusions Thyroid function tests had a limited association with tumoral characteristics