Efecto genotóxico de los compuestos orgánicos Benzo(a)pireno, Benzo(a)antraceno, Benzo(b)fluoranteno y Fenantreno del material particulado PM 2,5 del aire de la ciudad de Cuenca sobre células CHO-K1

Abstract

The industrialization and the increase of the automotive park, are fundamental factors for the formation of particulate material, which is considered, as one of the main responsible for the opportunity of human education. Being the main source of generation of particulate matter the incomplete combustion of vehicles with motor and diesel, because it favors the formation of police aromatic hydrocarbons, and what has been cataloged as carcinogenic and mutagenic substances according to the classification of the International Agency for Cancer Research (IARC). For this reason, the existence of hydrocarbons is considered: Benzo (a) pyrene, Benzo (a) anthracene Benzo (b) fluoranthene, and fluoranthene in particulate material PM 2,5 collected at monitored points in the city of Cuenca previously defined. Using gas chromatography coupled to masses, finding Benzo (a) Anthracene compound that assesses its potential damage can be transformed to the toxic concentration equivalent to Benzo (a) pyrotechnic value which was 0,001893 ng / m3 determined at point P1 in the Sangurima street between Benigno Malo and Luis Cordero. Being this considered as of low risk since it is below what has been published in different regions such as the European Commission (1 ng/m3). When performing the nonparametric statistical analysis of the comet assay cell viability deployment using the difference difference, in the direction of the tail of the cells. with those measures. The possibility of genetic damage at all monitored points.