Correlación entre el psa y el hallazgo histopatológico, en pacientes sometidos a biopsia transrectal de próstata guiada por ultrasonido en el diagnóstico de adenocarcinoma de próstata, Hospital José Carrasco Arteaga, Cuenca, Ecuador, 2017-2018

Abstract

Background: prostate cancer (PCa) is the most common malignancy in men, with high incidence and mortality rates. With the prostate-specific antigen (PSA) test, the detection and diagnosis of PAC increased, the place of detection of the pathology in the initial stages, and the improvement of prostate biopsy techniques, among other aspects. Objective: to determine the correlation of PSA and the histopathological finding in patients undergoing transrectal ultrasound-guided prostate biopsy and diagnosis of prostate adenocarcinoma, José Carrasco Arteaga Hospital, Cuenca, Ecuador, 2017-2018. Methodology: the sample size was 219 patients; the data were obtained from the medical records. A correlation study was carried out that compared the values of PSA with the histopathological finding of the patients who underwent a prostate biopsy guided by ultrasound in the period between January 2017 and July 2018, through statistical analysis Kappa de Cohen. Results: 66.7% of the patients were over 65 years of age, with an average age of 67.7 years. The prevalence of prostate cancer was 36.1%. The median PSA (15.40) between patients with and without cancer was statistically significant, with Mann Whitney U of 3330 and p-value: 0.000 (significance). The agreement was 0.24 with a p of 0.000 and this is acceptable. Conclusion: the PSA test in the diagnosis of prostate cancer was useful, being the transrectal biopsy of the prostate guided by ultrasound a support for its diagnosis