Por favor, use este identificador para citar o enlazar este ítem:
http://dspace.ucuenca.edu.ec/handle/123456789/29003
Exportar citación
Título : Ferritin levels and risk of metabolic syndrome: Meta-analysis of observational studies
Autor: Abril Ulloa, Sandra Victoria
Correspondencia: Arija, V.; Faculty of Medicine and Health Sciences, Universitat Rovira i Virgili, Reus, Spain; email: victoria.arija@urv.cat
Palabras clave : Ferritin Meta-Analysis Metabolic Syndrome
Fecha de publicación : 21-may-2014
Fecha de fin de embargo: 1-ene-2022
Volumen: 14
Fuente: BMC Public Health
metadata.dc.identifier.doi: 10.1186/1471-2458-14-483
Editor: BIOMED CENTRAL LTD.
Tipo: Article
Abstract: Background: Elevated ferritin levels have been associated with single cardiovascular risk factors but the relationship to the presence of metabolic syndrome is inconclusive.The aim of this systematic review and meta-analysis of published observational studies was to estimate the association between serum ferritin levels and metabolic syndrome in adults. Methods. The Pubmed, SCOPUS and the Cochrane Library databases were searched for epidemiological studies that assessed the association between ferritin levels and metabolic syndrome and were published before September 2013. There were no language restrictions. Two investigators independently selected eligible studies. Measures of association were pooled by using an inverse-variance weighted random-effects model. The heterogeneity among studies was examined using the I 2 index. Publication bias was evaluated using the funnel plot. Results: Twelve cross-sectional, one case-control and two prospective studies met our inclusion criteria including data from a total of 56,053 participants. The pooled odds ratio (OR) for the metabolic syndrome comparing the highest and lowest category of ferritin levels was 1.73 (95% CI: 1.54, 1.95; I2 = 75,4%). Subgroup analyses indicate that pooled OR was 1.92 (95% CI: 1.61, 2.30; I 2 = 78%) for studies adjusting for C-reactive protein (CRP), and 1.52 (95% CI:1. 36, 1.69; I2 = 41%) for studies that did not adjust for CRP (P = 0.044). This finding was remarkably robust in the sensitivity analysis. We did not find publication bias. Conclusions: The meta-analysis suggests that increased ferritin levels are independently and positively associated with the presence of the metabolic syndrome with an odds ratio higher than 1.73. © 2014Abril-Ulloa et al.; licensee BioMed Central Ltd.
URI : https://www.scopus.com/inward/record.uri?eid=2-s2.0-84902002885&doi=10.1186%2f1471-2458-14-483&partnerID=40&md5=5d2b70c02c0679795a5979a23dec1ca1 http://dspace.ucuenca.edu.ec/handle/123456789/29003
ISSN : 14712458
Aparece en las colecciones: Artículos
Este ítem está protegido por copyright original
Los ítems de DSpace están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.
Biblioteca Campus Central
Biblioteca Campus Salud
Biblioteca Campus Yanuncay
Av. 12 de Abril y Calle Agustín Cueva, Telf: 4051000 Ext. 1311, 1312, 1313, 1314. Horario de atención: Lunes-Viernes: 07H00-21H00. Sábados: 08H00-12H00
Av. El Paraíso 3-52, detrás del Hospital Regional "Vicente Corral Moscoso", Telf: 4051000 Ext. 3144. Horario de atención: Lunes-Viernes: 07H00-19H00
Av. 12 de Octubre y Diego de Tapia, antiguo Colegio Orientalista, Telf: 4051000 Ext. 3535 2810706 Ext. 116. Horario de atención: Lunes-Viernes: 07H30-19H00