Bioensayo toxicológico de paracetamol y remoción utilizando biosorción con bagazo de caña y membranas

Abstract

This work studies new technologies for the removal of paracetamol from aqueous solutions and the toxicity on the seeds of Lactuca Sativa. Sugar cane bagasse was used for column biosorption, and a 93.05% removal was found. A column modeling was performed, finding that the dose response model was the one that obtained the best adjustment with a 0.98 R2. Membrane technology of reverse osmosis and nanofiltration was used, finding a removal of 92.71% and 35.13% respectively. For the evaluation of toxicity, distilled water was used for testing, resulting on a 100% germination percentage. The seeds were exposed to synthetic solutions of paracetamol in concentrations of: 500, 250, 125, 62.5, 39, 19.5, 9.75, 6 and 1 mg/L; and at concentrations of: 100, 10, 1, 0.1, 0.01 μg/L, and a distilled water blank. The germination percentage for the blank was 100%, for 500 mg/L, 90%, and for the remaining concentrations there was no inhibition in germination. The inhibition percentage of hypocotyl and radicle in the mg/L range was 90.95% for hypocotyl and 87.59% for the radicle. The percentage of inhibition in the range of μg/L was also obtained for hypocotyl and radicle, with 19.28% for hypocotyl and 32.32% for radicle. The IC50 found for the radicle is 41.68 mg/L, and the IC50 of the hypocotyl is 62.17 mg/L. These results indicate that paracetamol causes hypocotyl and radicle inhibition.