Logo Repositorio Institucional

Por favor, use este identificador para citar o enlazar este ítem: http://dspace.ucuenca.edu.ec/handle/123456789/22042
Título : Ferritin levels and risk of metabolic syndrome: meta-analysis of observational studies
Otros títulos : BMC Public Health
Autor: Abril Ulloa, Sandra Victoria
Flores Mateo, Gemma
Solà Alberich, Rosa
Manuel-y-Keenoy, Begoña
Arija, Victoria
Palabras clave : Ferritin
Metabolic Syndrome
Meta-Analysis
Fecha de publicación : 2014
Paginación: Páginas 483
Numero / Secuencia : 
volumen 14
metadata.dc.identifier.doi: doi: doi:10.1186/1471-2458-14-483
Ciudad: 
Cuenca
Tipo: Article
Abstract: 
Background Elevated ferritin levels have been associated with single cardiovascular risk factors but the relationship to the presence of metabolic syndrome is inconclusive. The aim of this systematic review and meta-analysis of published observational studies was to estimate the association between serum ferritin levels and metabolic syndrome in adults. Methods The Pubmed, SCOPUS and the Cochrane Library databases were searched for epidemiological studies that assessed the association between ferritin levels and metabolic syndrome and were published before September 2013. There were no language restrictions. Two investigators independently selected eligible studies. Measures of association were pooled by using an inverse-variance weighted random-effects model. The heterogeneity among studies was examined using the I2 index. Publication bias was evaluated using the funnel plot. Results Twelve cross-sectional, one case–control and two prospective studies met our inclusion criteria including data from a total of 56,053 participants. The pooled odds ratio (OR) for the metabolic syndrome comparing the highest and lowest category of ferritin levels was 1.73 (95% CI: 1.54, 1.95; I2 = 75,4%). Subgroup analyses indicate that pooled OR was 1.92 (95% CI: 1.61, 2.30; I2 = 78%) for studies adjusting for C-reactive protein (CRP), and 1.52 (95% CI:1. 36, 1.69; I2 = 41%) for studies that did not adjust for CRP (P = 0.044). This finding was remarkably robust in the sensitivity analysis. We did not find publication bias. Conclusions The meta-analysis suggests that increased ferritin levels are independently and positively associated with the presence of the metabolic syndrome with an odds ratio higher than 1.73.
URI : http://dspace.ucuenca.edu.ec/handle/123456789/22042
Aparece en las colecciones: Artículos

Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
scopus 23.pdfdirección15.76 kBAdobe PDFVista previa
Visualizar/Abrir


Este ítem está protegido por copyright original



Este ítem está sujeto a una licencia Creative Commons Licencia Creative Commons Creative Commons

 

Centro de Documentacion Regional "Juan Bautista Vázquez"

Biblioteca Campus Central Biblioteca Campus Salud Biblioteca Campus Yanuncay
Av. 12 de Abril y Calle Agustín Cueva, Telf: 4051000 Ext. 1311, 1312, 1313, 1314. Horario de atención: Lunes-Viernes: 07H00-21H00. Sábados: 08H00-12H00 Av. El Paraíso 3-52, detrás del Hospital Regional "Vicente Corral Moscoso", Telf: 4051000 Ext. 3144. Horario de atención: Lunes-Viernes: 07H00-19H00 Av. 12 de Octubre y Diego de Tapia, antiguo Colegio Orientalista, Telf: 4051000 Ext. 3535 2810706 Ext. 116. Horario de atención: Lunes-Viernes: 07H30-19H00