Machado Orellana, Maria GabrielaOrellana Paucar, Adriana Monserrath2023-01-062023-01-0620221420-3049http://dspace.ucuenca.edu.ec/handle/123456789/40622https://www.scopus.com/record/display.uri?eid=2-s2.0-85137125184&doi=10.3390%2fmolecules27165055&origin=inward&txGid=f2bf66c642187d22a1a00a31d4572dd0The pharmacological attributes of turmeric have been extensively described and frequently related to the action of curcuminoids. However, there is also scientific evidence of the contribution of turmeric oil. Since the oil does not contain curcuminoids in its composition, it is crucial to better understand the therapeutic role of other constituents in turmeric. The present review discusses the pharmacokinetics of turmeric oil, pointing to the potential application of its active molecules as therapeutic compounds. In addition, the bioactivities of turmeric oil and its safety in preclinical and clinical studies were revised. This literature-based research intends to provide an updated overview to promote further research on turmeric oil and its constituents. © 2022 by the authors.es-ESCurcuma oilPharmacological activityToxicityTurmericTurmeric oilCurcuma longaSafetyPharmacological profileARTÍCULO10.3390/molecules27165055