Parkhouse, MichaelSciutto, EddaHernández, MariselaCortez, MariaCarpio Rodas, Luis ArturoFleury, Agnes2021-01-122021-01-12202001655728, e 1872-8421https://www.scopus.com/record/display.uri?eid=2-s2.0-85091217062&doi=10.1016%2fj.jneuroim.2020.577389&origin=inward&txGid=831beafae4a0d5a058f83bc579e79f18Neurocysticercosis (NC) presents two broad clinical entities: extraparenchymal (EP-NC) and parenchymal (P-NC). Using ELISA methodology, we demonstrate autoantibodies to tubulin and the Major oligodendrocyte glycoprotein (MOG) in the CSF of most, but not all, EP-NC samples. Levels of these autoantibodies were considerably reduced or absent in the P-NC samples. There was a striking correlation between levels of anti-tubulin and anti-MOG, and the significant correlation between the levels of autoantibodies and cellularity in the CSF, suggests that stimulation of the autoantibody response may be a function of cerebral inflammation. A hypothetical model to describe the pathogenesis of EP-NC is presentedes-ESNeurocysticercosisAnti-brain autoantibodiesTubulinMOGHP10ExtraparenchymalParenchymalARTÍCULO10.1016/j.jneuroim.2020.577389