Browsing by Author "Ochoa Castro, Maritza Raphaela"

Filter results by typing the first few letters
Now showing 1 - 2 of 2
  • Thumbnail Image
    Item
    Estudio de utilización de antibacterianos en las áreas de clínica y cirugía del hospital Vicente Corral Moscoso durante el período 2014 - 2018
    (Universidad de Cuenca, 2020-01-08) Arichávala Peña, Marcia Viviana; Campoverde Valdez, Guadalupe Rocío; Ochoa Castro, Maritza Raphaela
    The present study aims to determine the antibacterial of greater consumption in the Clinical and Surgery Areas of the "Vicente Corral Moscoso" Hospital during the 2014-2018 period. It was developed through a descriptive, longitudinal observational analysis with retrospective information collection, the methodology proposed by the World Health Organization (WHO) was used, based on the Anatomo-Chemical-Therapeutic Classification (ACT) in doses defined daily (DDD), as a technical unit of measurement and in the number DDD/100stances – day as a comparison parameter. For the statistical analysis, the Microsoft Office® Excel 2016 program (v16.0) was used. In the Clinic service the most consumed antibacterials during 2014 was ceftriaxone with 12.83DDD/stays-days, 2015 ampicillin + sulbactam with 5.78DDD/100stays-days, 2016 ceftriaxone with 5.80DDD/100stays-days, 2017 ampicillin + sulbactam with 5.63DDD/100stays-days and 2018 clarithromycin with 6.20DDD/stays-days. In the same way, in the department of Surgery it was cefazolin during the entire study period and considering an average use of 10.95100DDD/stay-days. The main use of cephalosporins was as a treatment for a variety of infectious diseases of the respiratory system, urinary tract, skin, soft tissues, joints, heart, etc., but especially in prevention and as prophylactic. This study of antibiotic consumption is very important in the pharmacoepidemiological area, in order to be used by other institutions and provides comparable data with similar entities nationally and internationally.
  • Thumbnail Image
    Item
    Incidencia de los niveles altos de transaminasas hepáticas en pacientes con artritis reumatoide que reciben metotrexato en el Hospital José Carrasco Arteaga, Cuenca
    (2016) Domínguez Vásquez, Olga Esther; Piedra Lozano, Gabriela Beatriz; Ochoa Castro, Maritza Raphaela
    Rheumatoid arthritis is a degenerative disease whose evolution causes the patient's life deterioration. Though it does not cause short-term mortality, it decreases quality of life .In order to control the degenerative process, Methotrexate is used as a disease-modifying anti-rheumatic drug. During this research, it has shown the incidence of elevated levels of liver transaminases due to the prolonged use of methotrexate in patients of both sexes, aged 20 to 80,so it was essential to review the medical records who came to the area of Rheumatology at Hospital José Carrasco Arteaga in the course of a year (August 2014 - August 2015) in the city of Cuenca. 78 patients who met the parameters established for this study were obtained. The incidence of patients with levels of alanine amino transferase above 41 IU, considered normal value, was 34.6%, close to 58% in men and 27% in women with significant differences in both groups (P = 0,0296). Regarding the enzyme aspartate amino transferase with normal values of 41 IU, it was observed levels above the normal range in approximately one of every four patients, and no significant differences according to sex. According to the results obtained in this research, it was confirmed the importance of Methotrexate in rheumatoid arthritis treatment due to prolonged administration, by causing an increase of transaminases.