Browsing by Author "Lopez Dominguez, Guillermo Estuardo"

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Evaluación del valor diagnóstico de la calprotectina fecal en pacientes con dispepsia
(2022) Gonzalez Dominguez, Camila Maria; Vasquez Moscoso, Ana Isabel; Cordova Reyes, Diego Andres; Abad Polo, Paula Gabriela; González, Juan Eduardo; Lopez Dominguez, Guillermo Estuardo; Cordero Asanza, Juan Jose; Gonzalez Dominguez, Esteban Horacio
The diagnosis of patients with dyspepsia represents a challenge since in most cases complex and costly endoscopic observations are required. In this study, we evaluated the diagnostic role of fecal calprotectin in patients with dyspepsia. To this end, an observational study was performed in 2019 on 149 patients with dyspepsia registered in the private Gastroenterology Specialists Center in Cuenca, Ecuador. The available data encompassed age, sex, alarm signs, fecal calprotectin (FC) values, and endoscopic findings. Patients in the age group >65 years were most represented, 56.4% of the population were female, 48.57% were FC positive of whom 86.8% possessed significant values of FC. FC+ was significantly associated with findings by EDA/colonoscopy (p<0.001). The most diagnostic pathologies in patients with FC+ were congestive gastropathy, intestinal metaplasia, giardiasis, and polyposis. FC correlated positively with the presence of pathological findings in the invasive diagnostic tests (r=0.298) and is a useful, noninvasive biomarker correlating positively with endoscopic findings in the gastrointestinal tract of dyspepsia patients.
Frecuencia de la intolerancia a la lactosa y síndrome de sobrecrecimiento bacteriano en pacientes con dispepsia sin signos de alarma. Estudio observacional descriptivo
(2023) Lopez Dominguez, Guillermo Estuardo
Introduction The prevalence and incidence of patients in private practice, presenting with dyspeptic symptoms as a chief complaint, is increasing, so we propose to determine the etiology in each patient, determining, lactose intolerance (LI) and intestinal bacterial overgrowth syndrome (SIBO), as the highest in prevalence. The exhaled H2 test is a practical and accessible method and has been validated in numerous studies as a diagnostic method. Objectives To establish the frequency of lactose intolerance and bacterial overgrowth in patients with dyspepsia without alarm signs in the Gastroenterology González specialty center in the city of Cuenca-Ecuador. Methodology This is a descriptive observational study, cross-sectional, which collected data through documentary analysis (medical records) and H2 exhaled test applied to 310 individuals of both sexes with an average age of 50±17 years, in the period February 2019 to February 2020. Results Lactose intolerance was observed in 29% of cases, while intestinal bacterial overgrowth in 20.3%.. Conclusions Lactose intolerance as well as bacterial overgrowth syndrome (SIBO), are frequent syndromes occurring in private practice, and should therefore be taken into account, when investigating a patient with dyspeptic symptoms, and should not be ruled out before performing a diagnostic test such as the exhaled H2 test.