Frecuencia de patrones de anticuerpos antinucleares ANA mediante inmunofluorescencia indirecta y su relación con el desarrollo de enfermedades autoinmunes en pacientes atendidos en el Hospital Vicente Corral Moscoso. enero 2019 - diciembre 2020.

Abstract

Background: autoimmune diseases affect 3-5% of the general population, the scarce regional and diagnostic information has generated a low epidemiological index. Antinuclear antibodies ANA have a high frequency in autoimmune diseases, their identification by automated indirect immunofluorescence provides useful information in the diagnosis and follow-up of the patient. Objective: to determine the frequency of antinuclear antibody ANA patterns by indirect immunofluorescence and its relationship with the development of autoimmune diseases in patients treated at the Vicente Corral Moscoso Hospital. January 2019 - december 2020. Methodology: a retrospective descriptive study was carried out; the universe was made up of patients diagnosed with autoimmune diseases treated at the Vicente Corral Moscoso Hospital. The information was interpreted through tables and statistical graphs using Excel, IBM SPSS programs for data analysis and tabulation. Results: the frequency of antinuclear antibodies ANA was 19,83%; a predominance of the female sex (89,72%) was observed, as well as the age group between 27 to 64 years (66,18%). In the study population, the most frequent pattern was nuclear fine speckled AC-4 (26,57%) and the most frequent autoimmune disease was systemic lupus erythematosus (45,41%). Conclusion: in the study population, it was observed that the highest frequency of positive antinuclear antibodies ANA was in females, in adulthood, the most common pattern was nuclear fine speckled AC-4, which was related to systemic lupus erythematosus.