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DC Field | Value | Language |
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dc.contributor.author | Parkhouse, Michael | - |
dc.contributor.author | Sciutto, Edda | - |
dc.contributor.author | Hernández, Marisela | - |
dc.contributor.author | Cortez, Maria | - |
dc.contributor.author | Carpio Rodas, Luis Arturo | - |
dc.contributor.author | Fleury, Agnes | - |
dc.date.accessioned | 2021-01-12T17:24:27Z | - |
dc.date.available | 2021-01-12T17:24:27Z | - |
dc.date.issued | 2020 | - |
dc.identifier.issn | 01655728, e 1872-8421 | - |
dc.identifier.uri | https://www.scopus.com/record/display.uri?eid=2-s2.0-85091217062&doi=10.1016%2fj.jneuroim.2020.577389&origin=inward&txGid=831beafae4a0d5a058f83bc579e79f18 | - |
dc.description.abstract | Neurocysticercosis (NC) presents two broad clinical entities: extraparenchymal (EP-NC) and parenchymal (P-NC). Using ELISA methodology, we demonstrate autoantibodies to tubulin and the Major oligodendrocyte glycoprotein (MOG) in the CSF of most, but not all, EP-NC samples. Levels of these autoantibodies were considerably reduced or absent in the P-NC samples. There was a striking correlation between levels of anti-tubulin and anti-MOG, and the significant correlation between the levels of autoantibodies and cellularity in the CSF, suggests that stimulation of the autoantibody response may be a function of cerebral inflammation. A hypothetical model to describe the pathogenesis of EP-NC is presented | - |
dc.language.iso | es_ES | - |
dc.source | Journal of Neuroimmunology | - |
dc.subject | Neurocysticercosis | - |
dc.subject | Anti-brain autoantibodies | - |
dc.subject | Tubulin | - |
dc.subject | MOGHP10 | - |
dc.subject | Extraparenchymal | - |
dc.subject | Parenchymal | - |
dc.title | Extraparenchymal human neurocysticercosis induces autoantibodies against brain tubulin and MOG35–55 in cerebral spinal fluid | - |
dc.type | ARTÍCULO | - |
dc.ucuenca.idautor | Sgrp-4026-01 | - |
dc.ucuenca.idautor | 0000-0001-5608-5355 | - |
dc.ucuenca.idautor | Sgrp-4026-03 | - |
dc.ucuenca.idautor | Sgrp-4026-04 | - |
dc.ucuenca.idautor | 0100737956 | - |
dc.ucuenca.idautor | 0000-0002-8930-2202 | - |
dc.identifier.doi | 10.1016/j.jneuroim.2020.577389 | - |
dc.ucuenca.version | Versión publicada | - |
dc.ucuenca.areaconocimientounescoamplio | 09 - Salud y Bienestar | - |
dc.ucuenca.afiliacion | Parkhouse, M., Instituto de Ciencias Gulbenkian, Oeiras, Portugal | - |
dc.ucuenca.afiliacion | Sciutto, E., Universidad Nacional Autonoma de Mexico, Mexico City, Mexico | - |
dc.ucuenca.afiliacion | Hernández, M., Universidad Nacional Autonoma de Mexico, Mexico City, Mexico | - |
dc.ucuenca.afiliacion | Cortez, M., Universidad de Carabobo, Valencia, Venezuela | - |
dc.ucuenca.afiliacion | Carpio, L., Columbia University, New York, Estados unidos; Carpio, L., Universidad de Cuenca, Facultad de Ciencias Médicas, Cuenca, Ecuador | - |
dc.ucuenca.afiliacion | Fleury, A., Universidad Nacional Autonoma de Mexico, Mexico City, Mexico; Fleury, A., Instituto Nacional de Neurologia y Neurocirugia, Tlalpan, Mexico | - |
dc.ucuenca.correspondencia | Parkhouse, Michael, parkhous@igc.gulbenkian.pt | - |
dc.ucuenca.volumen | Volumen 349 | - |
dc.ucuenca.indicebibliografico | SCOPUS | - |
dc.ucuenca.factorimpacto | 0.837 | - |
dc.ucuenca.cuartil | Q2 | - |
dc.ucuenca.numerocitaciones | 0 | - |
dc.ucuenca.areaconocimientofrascatiamplio | 3. Ciencias Médicas y de la Salud | - |
dc.ucuenca.areaconocimientofrascatiespecifico | 3.3 Ciencias de la Salud | - |
dc.ucuenca.areaconocimientofrascatidetallado | 3.3.9 Enfermedades Infecciosas | - |
dc.ucuenca.areaconocimientounescoespecifico | 091 - Salud | - |
dc.ucuenca.areaconocimientounescodetallado | 0912 - Medicina | - |
dc.ucuenca.urifuente | https://www.sciencedirect.com/journal/journal-of-neuroimmunology/vol/349/suppl/C | - |
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