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DC Field | Value | Language |
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dc.contributor.author | Rodriguez Coyago, Maria De lourdes | - |
dc.contributor.author | Alcira C, Rosa | - |
dc.contributor.author | Rodríguez, Jennifer | - |
dc.contributor.author | Nastri, María | - |
dc.contributor.author | Jewtuchowicz, Virginia | - |
dc.date.accessioned | 2020-10-26T04:13:24Z | - |
dc.date.available | 2020-10-26T04:13:24Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 2398-6700 | - |
dc.identifier.uri | http://verizonaonlinepublishing.com/PDF/Dental/JournalofDentalScienceandTherapy15.pdf | - |
dc.description | null | - |
dc.description.abstract | The Candida parapsilosis complex comprises three genetically related species: Candida parapsilosis sensu stricto, Candida orthopsilosis and Candida metapsilosis. During the last decade, Candida parapsilosis sensu stricto has become the second most commonly isolated yeast from patients with blood stream invasive fungal infections, following Candida albicans. Despite its clinical significance, little is known about its distribution and behavior in oral cavity niches. Given this background, we intended to perform a molecular characterization of 38 isolates of the Candida parapsilosis complex collected from oral cavities of immunocompetent patients with and without gingival- periodontal disease, with the aim of determining its distribution and establishing a correlation with clinical data. Besides, we assessed the virulence of the strains by examining the in vitro biofilm-forming capacity in two different culture media: YPD and RPMI 1640. Being more frequently isolated from oral cavities with pathological conditions, 89.5% of the strains were reconfirmed to be Candida parapsilosis sensu stricto. More than 70% of the Candida parapsilosis sensu stricto strains showed biofilm-forming capacity in both culture media, reflecting a statistically significant association between biofilm-forming capacity and the clinical conditions of the subjects from whom the strains were isolated. Among the three complex species, Candida parapsilosis sensu stricto is a normal commensal in the oral cavity, being more frequently recovered in inflammatory conditions. Gingival-periodontal disease may be a factor triggering overgrowth and virulence of Candida parapsilosis sensu stricto commensal strains. | - |
dc.language.iso | es_ES | - |
dc.source | Journal of Dental Science and Therapy | - |
dc.subject | Candida parapsilosis complex | - |
dc.subject | Candida parapsilosis sensu stricto | - |
dc.subject | Oral colonization | - |
dc.subject | Biofilm | - |
dc.subject | Gingival periodontal disease | - |
dc.title | The oral cavity: a reservoir that favors colonization and selection of candida parapsilosis sensu stricto strains with high pathogen potential under conditions of gingival-periodontal disease | - |
dc.title.alternative | null | - |
dc.type | ARTÍCULO | - |
dc.ucuenca.idautor | 0704480276 | - |
dc.ucuenca.idautor | sgrp-3259-002 | - |
dc.ucuenca.idautor | sgrp-3259-003 | - |
dc.ucuenca.idautor | sgrp-3259-004 | - |
dc.ucuenca.idautor | sgrp-3260-002 | - |
dc.ucuenca.version | Versión publicada | - |
dc.ucuenca.areaconocimientounescoamplio | 09 - Salud y Bienestar | - |
dc.ucuenca.afiliacion | Rodriguez, M., Universidad de Cuenca, Facultad de Odontología, Cuenca, Ecuador; Rodriguez, M., Buenos Aires University, Buenos Aires, Argentina | - |
dc.ucuenca.afiliacion | Alcira, R., Buenos Aires University, Buenos Aires, Argentina | - |
dc.ucuenca.afiliacion | Rodríguez, J., Instituto Ecuatoriano de Seguridad Social, Guayaquil, Ecuador | - |
dc.ucuenca.afiliacion | Nastri, M., Buenos Aires University, Buenos Aires, Argentina | - |
dc.ucuenca.afiliacion | Jewtuchowicz, V., Buenos Aires University, Buenos Aires, Argentina | - |
dc.ucuenca.correspondencia | Rodriguez Coyago, Maria De lourdes, maria.rodriguezc84@ucuenca.edu.ec | - |
dc.ucuenca.volumen | Volumen 2, número 1 | - |
dc.ucuenca.indicebibliografico | SIN INDEXAR | - |
dc.ucuenca.numerocitaciones | 0 | - |
dc.ucuenca.areaconocimientofrascatiamplio | 1. Ciencias Naturales y Exactas | - |
dc.ucuenca.areaconocimientofrascatiespecifico | 1.6 Ciencias Biológicas | - |
dc.ucuenca.areaconocimientofrascatidetallado | 1.6.2 Microbiología | - |
dc.ucuenca.areaconocimientounescoespecifico | 091 - Salud | - |
dc.ucuenca.areaconocimientounescodetallado | 0912 - Medicina | - |
dc.ucuenca.urifuente | http://verizonaonlinepublishing.com/JournalofDentalScienceandTherapy.aspx | - |
Appears in Collections: | Artículos |
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documento.pdf | document | 577.92 kB | Adobe PDF | View/Open |
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