Prevalencia de hipotiroidismo sub clínico y clínico y su asociación con el síndrome metabólico, Pablo Jaramillo Cuenca, 2016

Abstract

background: hypothyroidism is associated with cardiovascular diseases, however, studies that demonstrate the association with metabolic syndrome reveal different results. Objectives: To determine the prevalence of clinical and clinical sub hypothyroidism and its association with the metabolic syndrome in people between 40-65 years of age, who go to outpatient clinic at the Pablo Jaramillo Foundation in the city of Cuenca during 2016. Materials and methods: A cross-sectional study was carried out. 256 patients were included, according to a 10% expected frequency, with a 95% confidence level, and a margin of error of 4%, whom attended the Pablo Jaramillo Foundation in Cuenca. Clinical, anthropometric and laboratory assessment (TSH, glucose, HDL and triglyceride levels) were performed. The components of the Metabolic Syndrome were graded according to the ALAD / GLESMO / IDF harmonized criteria. Results: the study group consisted of 79.3% of female patients. The prevalence of hypothyroidism was 37.8% with a 95% CI 31.7-44, with the most frequent subclinical presentation being 31%. The association between hypothyroidism and metabolic syndrome was established by obtaining an RP of 2.5; with a 95% CI 1.30-3.57; (P <0.02). From the criteria of the metabolic syndrome, a statistically significant association was found between hypothyroid patients and those with triglyceride values >150mg / dl with a PR of 1.26 and 95% CI 1.05-1.51; (P <0.01). Conclusions: the prevalence of the two pathologies is higher than expected; Hypothyroidism is associated with the metabolic syndrome