Frecuencia y características de las alteraciones del perfil lipídico en pacientes con hipotiroidismo subclínico en el Hospital Vicente Corral Moscoso, Cuenca-Ecuador 2016

Abstract

Due to the increase of diagnosis of subclinical hypothyroidism in the last years, studies have been carried out to demonstrate the alteration of the lipid profile in these patients. There are statistically significant alterations in some, while in others the relationship has not been established. Objectives To determine the frequency and characteristics of alterations in the lipid profile of patients with subclinical hypothyroidism at the Hospital Vicente Corral Moscoso, Cuenca-Ecuador 2016. Methodology Descriptive study with a sample of 89 patients with Subclinical Hypothyroidism. The data was registered in a data form according to the clinical records and laboratory tests of patients who were attended in 2016, either by control or new diagnosis. A database was developed in the program SPSS version 15. The analyzed variables were: TSH, free T3, free T4, total cholesterol, LDL, HDL, triglycerides, nutritional status, sex, age and habit of smoking. The data was processed using frequency distribution, mean and standard diverted. The information was presented in tables and graphs. Results At the end of the study, 42 (47.2%) out of the 89 patients presented alterations in total cholesterol level, while 47 (52.8%) did not; 55.1% (49) showed alterations in HDL, while 44.9% did not; 9 patients (10.1%) had alterations in LDL and 80 (89.9%) maintained normal levels; and 44 (49.4%) had alterations in triglycerides, while 45 patients (50.6%) did not. Conclusion The frequency of alterations in the lipid profile of patients with subclinical hypothyroidism, who were attended in the Endocrinology Service at the Hospital Vicente Corral Moscoso, changes according to the lipid. However, the lipid which presents more alterations is HDL, then triglycerides, cholesterol and at the last LDL