Prevalencia de sepsis precoz confirmada por hemocultivo y relación por score predictivo de sepsis en recién nacidos con factores de riesgo maternos en el Hospital Vicente Corral Moscoso, Cuenca 2014

Abstract

Background: Systematic bacterial infections represent an important cause of neonatal morbid mortality; these have been associated with maternal factors. This study will focus in its identification and analysis. Objective: Determining the prevalence or premature sepsis confirmed by blood cultures and its relationship with predictive sepsis score in newborns with maternal risk factors in Vicente Corral Moscoso Hospital. Methodology: A transversal study reviewing 1327 medical records that include 261 cases with maternal risk factors for sepsis. The necessary registered information on the forms was obtained through medical records. The study analyzes: relative frequencies, percentages, mediums, standard deviation, chi square and measuring the odds ratio effect with 95% confidence interval. Results: The prevalence of sepsis according to positive blood cultures was 34% in the population with risk factors. In total newborns was 0.67%. according to the sepsis score 16.2% of neonates with sepsis risk factors presented probable sepsis; the most frequently isolated germ was Staphylococcus coagulase negative with 77.8%; the frequency of antibiotic usage was 34.1%; the most frequent risk factors were: UTI 62,8%, bacterial vaginosis 22,6%, premature rupture of membranes greater than 18 hours with OR 5,1 (95% CI 1,3 to 20). The score sensitivity was 77,78 % and specificity of 86,1%. In the cases classified as probable sepsis 16,7% were confirmed by blood culture. Conclusions: premature rupture of membranes represents the major risk factor for sepsis in this study. UTI is the most frequent risk factor. The antibiotic usage is high in relation to the number of patients with pathological complete blood count.