Control HSMC para regulación de glucosa sanguínea

Abstract

This article proposes a new strategy of control based on continue measurements of glucose and a habituating sliding mode controller (HSMC). The HSMC is developed combining the sliding mode control law and the principles of habituating control. The HSMC applied to the regulation of blood glucose in the intensive care unit, includes both intravascular glucose and insulin infusion inputs to provide the nutrition supply and to improve the rejection to disturbances. The simulation based study (in silico), using a physiological model of the dynamic glucose-insulin, shows that proposed control strategy works properly. Finally, the performance of the proposed controller and a standard PID controller are compared.